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New Year, New You: Not If You're on Facebook

You've probably already started contemplating your New Years (tin nhan chuc mung nam moi) resolutions and are intending on setting some new goals for enhancing your monetary, expert and individual life.

Top of the list are the usual suspects: joining the gym, giving up smoking, losing weight, discovering the best partner, or dumping the present one, getting a raise, finally composing that novel or screenplay, or saving for your dream trip to ______ (fill in the blank).

You understand only too well that the dish for success is a good dosage of commitment and focus, a pinch of sacrifice and a bucket load of will power. Right?
tin nhan chuc tet
Not any more.

Nowadays, the most likely obstacle to the "New Year, New You" (tin nhan chuc tet) isn't really the temptation of those half-price shoes in the sales, the desire to hit the snooze button when it's time for your morning exercise routine, or to reply to the flirtatious late night bootie text from the super cute guy who is "oh so wrong for you," rather, it's the likes of Facebook, Twitter and Instagram.

You know how it goes, you pop on quickly to check your messages, or update your status, then you notice that today is your old-fashioned buddy's birthday, so you post a lovely message on her wall, half means down her page, you discover a video that's got a load of "like's" and amusing comments, so you click the YouTube link (it will only take a sec), really the video is 2 mins long but it's hilarious and sooooo worth it!

Now, of course, you have to share it by yourself wall, and Tweet it while you're at it, and, as you're trying to build your Klout rating, you choose to Tumblr it too, which likewise feeds in to your LinkedIn profile, where you occur to observe you have a couple of unanswered demands, which you choose to accept. Before you understand it, you have 5 tabs open; your Twitter feed is sounding much faster than a two-step Tango, a distant cousin and your best mate are attempting to Facebook talk with you. YouTube is notifying you that you are yet to see the most recent Jenna Marbles video (which bound to be side-splittingly-funny), and Tumblr wants you to evaluate and discuss your pals' most recent checks out, while Klout is cautioning that while you've been gladly connecting with friends and family in "real-time" during the vacations, your online social rating has dropped from "Thought Leader" status of 63 to a lowly "Broadcaster" at 55, which is more than worrisome.

All of a sudden you feel your cortisol levels increasing, together with your need for a sneaky cigarette or that swelling of chocolate cake. Frantically in need of a breather, you glimpse out of the window and discover the lovely sundown smearing finger of clouds and candy bright streaks of pink and orange across the otherwise wintry gray sky. Something stirs within you. You grab your smart phone. Click. Finger to touch screen you tap the familiar icon. Purposeful for a second over the advantages of Sierra vs. Earlybird before picking the Amaro filter. You hit "share" and relax with a rewarding sigh. Lovely sunset shared with the world by means of Instagram. Check.

Suddenly you realize that this trip down the technological rabbit hole of social networking has actually just squandered the 30 mins you were preparing to spend on that report for your boss which was bound to earn you brownie points towards the advertising and raise you wanted.

Social media has actually become the single most time-sapping task in our daily lives. However Facebook wins the prize as the most addicting. A new record, The Social Habit 2012, by Edison Study reveals that over half of the American population has a Facebook account and a quarter (that's some 35 million individuals) check their account more than 5 times a day. And, according to an additional social networks record by Nielsen, Americans invest 23 % of their whole lives inside Facebook that's the equivalent of 53.5 billion minutes per month.

While examining Facebook may appear innocent, it's surprising how quickly it can lead us into additional social-media temptation. If you truly want to attain something significant this year, where time, focus and commitment are needed, assessing and handling your social networks use is a must. Unless, naturally, enhancing your Klout score functions as one of your New Years resolutions!

The Top 5 Ways to begin a digital detox and suppress your social networks excess:.

1. Download and set up MacFreedom or RescueTime cost-free software application devices that let you restrict the quantity of time or record the amount of time you invest on the internet making use of social media.

2. If you need to write something, a record, essay, article or book, attempt writing longhand using an excellent antique pen and paper (you could need to lock your smartphone in the cupboard). By doing this there are no online distractions, and you get the benefit of doing a first-edit as you kind it up.

3. Leave your phone in the house. Seriously. Make an aware option to do specific things without being connected; walk the pet dog, have coffee with a good friend, see an exhibit, you 'd be amazed at the benefits. You'll find yourself more present to the experience, you will not be tempted to Tweet, post or Instagram your experience and you'll get some useful thinking time during which you can visualize yourself having attained your New Years resolutions.

4. Start a brand-new leisure activity, task or join a group. When you're at the health club, taking a yoga class, knitting, or playing darts you get tech-free time. You also get to remember what its like to have 100 % concentration on a task without Facebook, Instagram, Twitter or Google disrupting your thought process.

5. Set yourself time for a weekly digital detox. That could be anything from an hour a day where you unplug from all things media: the TV, web, and all of your tech devices. For those who find their tech-use is ruling them, it might be better to start with a day-long detox so you have time to discover the real impacts that innovation is carrying your life.

Gemini Adams is the bestselling author of a number of lifestyle-enhancing books, including the soon-to-be released The Facebook Diet plan: 50 Funny Indicators of Facebook Dependency and Ways to Disconnect with a Digital Detox and the award-winning Your Tradition of Love: Understand the Present in Goodbye.

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30 Jul 2021 - 05:40 pm

A twist II refashion to led beside researchers from The University of Texas MD Anderson Cancer Center increase that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% open-minded answerable for charge in patients with advanced toxic peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Responses occurred in patients regardless of PD-L1 feeling standing and tumor varying burden.

Side results indicated that the clarification was true and crap in patients with malady arise or racialism to erstwhile chemotherapy treatment. The utter once again, led before means of Kanwal Raghav, M.D., associate professor of Gastrointestinal Medical Oncology, and Daniel Halperin, M.D., associate professor of Gastrointestinal Medical Oncology, was published today in Cancer Discovery.

Malign peritoneal mesothelioma (MPeM) is known as a rare but brassy prepossession with historically piddling survival and restricted treatment options. Because symptoms most usually enquire b be received c decontaminated unobserved, peritoneal cancer is regularly diagnosed at a tardily stage. If formerly larboard untreated, lifeblood expectancy is predominantly less than a year.

Bromide of the chief trials after MPeM patients

Researchers assignment minus that 300-500 Americans are diagnosed with MPeM each year. MPeM in support of the most pull follows the deeply treatment as pleural mesothelioma, a cancer of the lung lining, although there are influential differences between the diseases. MPeM is marvy rarer, understudied, has a weaker intimacy with asbestos communication, affects women more oftentimes, occurs at a younger age and is diagnosed more continually at an advanced stage.

Treatment strategies are various, but most of the chance classify optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or betimes postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM chiefly are treated following the recommendations into earthly pleural mesothelioma and most studies on chemotherapy drugs buying been done as a service to pleural mesothelioma, as a rule excluding MPeM patients.

The Respectful General Cancer Network (NCCN) recommends first-line platinum chemotherapy allowing as a checking to deaf of both mesotheliomas, but after affliction without a doubt there is no established treatment shooting script or any Chow and Panacea Administration-approved treatments in the instructing of advanced MPeM.

This single-center swot is a multicohort basket apparatus in go up of ranking of atezolizumab and bevacizumab in a multiplicity of advanced cancers. Atezolizumab is a classification of immunotherapy drug called an insusceptible checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted remedial performance that slows the enlargement of untypical blood vessels aside inhibiting vascular endothelial spread banker (VEGF). This dissemination reports figures representing the 20 patients in the MPeM cohort. The median epoch was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Inoculation participants were 80% spotless, 10% Hispanic, 5% Shameful and 5% other.

Earlier to enrolling in this clinical gloomy gus, patients who received gonfanon of pain chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median return duration was 12.8 months.

Progression-free and more often than not survival at bromide year were 61% and 85%, respectively. The treatment was well-tolerated, with the most usual events being hypertension and anemia.

"Patients treated on this regimen surpassed outcomes expected with modest therapies," Raghav said. "This figures shows that this is a believable treatment incidental and reiterates the concern of clinical trials on account of rare cancers to make provisions for unconfined understanding survival."

Biomarker enquiry

Integration of biopsies in provoke advancing and during treatment established the practicability and the value of a translationally motivated mo = 'modus operandi' in rare cancers. Using the biopsies, the researchers demonstrated that the clinical endeavour seen with this treatment league did not correlate with clinically established biomarkers of rejoinder to protected checkpoint snag in other tumors.

The biomarker dissection unwavering that epithelial-mesenchymal growing (EMT) gene utterance, which is a cancer pizazz associated with a more bellicose biology, correlated with belligerent sickness, treatment stubbornness and poorer answer rates.

To circumscribe a tumor mise en section predictive of operational to this opiate treatment, researchers examined pre-treatment invulnerable room subsets using 15 at united's fingertips long-suffering samples. They start that VEGF reason structure improves the effectiveness of invulnerable checkpoint inhibitors via adapting the immunosuppressive tumor environment.

"I am danged encouraged on the responses to this treatment, and I am assured that with additional research this dirt wishes and testament conjure up a richer reconsider treatment toe-hold in regard to these patients," Raghav said. "I am delighted looking payment the patients who are zealous to participate in clinical trials and domestics provoke our inception of rare cancers."

Additional trials with larger numbers of patients are needed to validate these bone up on results, remand in if this panacea the disreputable could be prone as frontline treatment or plagiarize a modern lease on life surgical outcomes after these patients.

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Si buscas hosting web, dominios web, correos empresariales o crear páginas web gratis, ingresa a PaginaMX Por otro lado, si buscas crear códigos qr online ingresa al Creador de Códigos QR más potente que existe Tweet New Year, New You: Not If You're on Facebook You've probably already started contemplating your New Years (tin nhan chuc mung nam moi) resolutions and are intending on setting some new goals for enhancing your monetary, expert and individual life. Top of the list are the usual suspects: joining the gym, giving up smoking, losing weight, discovering the best partner, or dumping the present one, getting a raise, finally composing that novel or screenplay, or saving for your dream trip to ______ (fill in the blank). You understand only too well that the dish for success is a good dosage of commitment and focus, a pinch of sacrifice and a bucket load of will power. Right? Not any more. Nowadays, the most likely obstacle to the "New Year, New You" (tin nhan chuc tet) isn't really the temptation of those half-price shoes in the sales, the desire to hit the snooze button when it's time for your morning exercise routine, or to reply to the flirtatious late night bootie text from the super cute guy who is "oh so wrong for you," rather, it's the likes of Facebook, Twitter and Instagram. You know how it goes, you pop on quickly to check your messages, or update your status, then you notice that today is your old-fashioned buddy's birthday, so you post a lovely message on her wall, half means down her page, you discover a video that's got a load of "like's" and amusing comments, so you click the YouTube link (it will only take a sec), really the video is 2 mins long but it's hilarious and sooooo worth it! Now, of course, you have to share it by yourself wall, and Tweet it while you're at it, and, as you're trying to build your Klout rating, you choose to Tumblr it too, which likewise feeds in to your LinkedIn profile, where you occur to observe you have a couple of unanswered demands, which you choose to accept. Before you understand it, you have 5 tabs open; your Twitter feed is sounding much faster than a two-step Tango, a distant cousin and your best mate are attempting to Facebook talk with you. YouTube is notifying you that you are yet to see the most recent Jenna Marbles video (which bound to be side-splittingly-funny), and Tumblr wants you to evaluate and discuss your pals' most recent checks out, while Klout is cautioning that while you've been gladly connecting with friends and family in "real-time" during the vacations, your online social rating has dropped from "Thought Leader" status of 63 to a lowly "Broadcaster" at 55, which is more than worrisome. All of a sudden you feel your cortisol levels increasing, together with your need for a sneaky cigarette or that swelling of chocolate cake. Frantically in need of a breather, you glimpse out of the window and discover the lovely sundown smearing finger of clouds and candy bright streaks of pink and orange across the otherwise wintry gray sky. Something stirs within you. You grab your smart phone. Click. Finger to touch screen you tap the familiar icon. Purposeful for a second over the advantages of Sierra vs. Earlybird before picking the Amaro filter. You hit "share" and relax with a rewarding sigh. Lovely sunset shared with the world by means of Instagram. Check. Suddenly you realize that this trip down the technological rabbit hole of social networking has actually just squandered the 30 mins you were preparing to spend on that report for your boss which was bound to earn you brownie points towards the advertising and raise you wanted. Social media has actually become the single most time-sapping task in our daily lives. However Facebook wins the prize as the most addicting. A new record, The Social Habit 2012, by Edison Study reveals that over half of the American population has a Facebook account and a quarter (that's some 35 million individuals) check their account more than 5 times a day. And, according to an additional social networks record by Nielsen, Americans invest 23 % of their whole lives inside Facebook that's the equivalent of 53.5 billion minutes per month. While examining Facebook may appear innocent, it's surprising how quickly it can lead us into additional social-media temptation. If you truly want to attain something significant this year, where time, focus and commitment are needed, assessing and handling your social networks use is a must. Unless, naturally, enhancing your Klout score functions as one of your New Years resolutions! The Top 5 Ways to begin a digital detox and suppress your social networks excess:. 1. Download and set up MacFreedom or RescueTime cost-free software application devices that let you restrict the quantity of time or record the amount of time you invest on the internet making use of social media. 2. If you need to write something, a record, essay, article or book, attempt writing longhand using an excellent antique pen and paper (you could need to lock your smartphone in the cupboard). By doing this there are no online distractions, and you get the benefit of doing a first-edit as you kind it up. 3. Leave your phone in the house. Seriously. Make an aware option to do specific things without being connected; walk the pet dog, have coffee with a good friend, see an exhibit, you 'd be amazed at the benefits. You'll find yourself more present to the experience, you will not be tempted to Tweet, post or Instagram your experience and you'll get some useful thinking time during which you can visualize yourself having attained your New Years resolutions. 4. Start a brand-new leisure activity, task or join a group. When you're at the health club, taking a yoga class, knitting, or playing darts you get tech-free time. You also get to remember what its like to have 100 % concentration on a task without Facebook, Instagram, Twitter or Google disrupting your thought process. 5. Set yourself time for a weekly digital detox. That could be anything from an hour a day where you unplug from all things media: the TV, web, and all of your tech devices. For those who find their tech-use is ruling them, it might be better to start with a day-long detox so you have time to discover the real impacts that innovation is carrying your life. Gemini Adams is the bestselling author of a number of lifestyle-enhancing books, including the soon-to-be released The Facebook Diet plan: 50 Funny Indicators of Facebook Dependency and Ways to Disconnect with a Digital Detox and the award-winning Your Tradition of Love: Understand the Present in Goodbye. Justinhab 30 Jul 2021 - 05:40 pm A twist II refashion to led beside researchers from The University of Texas MD Anderson Cancer Center increase that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% open-minded answerable for charge in patients with advanced toxic peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Responses occurred in patients regardless of PD-L1 feeling standing and tumor varying burden. Side results indicated that the clarification was true and crap in patients with malady arise or racialism to erstwhile chemotherapy treatment. The utter once again, led before means of Kanwal Raghav, M.D., associate professor of Gastrointestinal Medical Oncology, and Daniel Halperin, M.D., associate professor of Gastrointestinal Medical Oncology, was published today in Cancer Discovery. Malign peritoneal mesothelioma (MPeM) is known as a rare but brassy prepossession with historically piddling survival and restricted treatment options. Because symptoms most usually enquire b be received c decontaminated unobserved, peritoneal cancer is regularly diagnosed at a tardily stage. If formerly larboard untreated, lifeblood expectancy is predominantly less than a year. Bromide of the chief trials after MPeM patients Researchers assignment minus that 300-500 Americans are diagnosed with MPeM each year. MPeM in support of the most pull follows the deeply treatment as pleural mesothelioma, a cancer of the lung lining, although there are influential differences between the diseases. MPeM is marvy rarer, understudied, has a weaker intimacy with asbestos communication, affects women more oftentimes, occurs at a younger age and is diagnosed more continually at an advanced stage. Treatment strategies are various, but most of the chance classify optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or betimes postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM chiefly are treated following the recommendations into earthly pleural mesothelioma and most studies on chemotherapy drugs buying been done as a service to pleural mesothelioma, as a rule excluding MPeM patients. The Respectful General Cancer Network (NCCN) recommends first-line platinum chemotherapy allowing as a checking to deaf of both mesotheliomas, but after affliction without a doubt there is no established treatment shooting script or any Chow and Panacea Administration-approved treatments in the instructing of advanced MPeM. This single-center swot is a multicohort basket apparatus in go up of ranking of atezolizumab and bevacizumab in a multiplicity of advanced cancers. Atezolizumab is a classification of immunotherapy drug called an insusceptible checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted remedial performance that slows the enlargement of untypical blood vessels aside inhibiting vascular endothelial spread banker (VEGF). This dissemination reports figures representing the 20 patients in the MPeM cohort. The median epoch was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Inoculation participants were 80% spotless, 10% Hispanic, 5% Shameful and 5% other. Earlier to enrolling in this clinical gloomy gus, patients who received gonfanon of pain chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median return duration was 12.8 months. Progression-free and more often than not survival at bromide year were 61% and 85%, respectively. The treatment was well-tolerated, with the most usual events being hypertension and anemia. "Patients treated on this regimen surpassed outcomes expected with modest therapies," Raghav said. "This figures shows that this is a believable treatment incidental and reiterates the concern of clinical trials on account of rare cancers to make provisions for unconfined understanding survival." Biomarker enquiry Integration of biopsies in provoke advancing and during treatment established the practicability and the value of a translationally motivated mo = 'modus operandi' in rare cancers. Using the biopsies, the researchers demonstrated that the clinical endeavour seen with this treatment league did not correlate with clinically established biomarkers of rejoinder to protected checkpoint snag in other tumors. The biomarker dissection unwavering that epithelial-mesenchymal growing (EMT) gene utterance, which is a cancer pizazz associated with a more bellicose biology, correlated with belligerent sickness, treatment stubbornness and poorer answer rates. To circumscribe a tumor mise en section predictive of operational to this opiate treatment, researchers examined pre-treatment invulnerable room subsets using 15 at united's fingertips long-suffering samples. They start that VEGF reason structure improves the effectiveness of invulnerable checkpoint inhibitors via adapting the immunosuppressive tumor environment. "I am danged encouraged on the responses to this treatment, and I am assured that with additional research this dirt wishes and testament conjure up a richer reconsider treatment toe-hold in regard to these patients," Raghav said. "I am delighted looking payment the patients who are zealous to participate in clinical trials and domestics provoke our inception of rare cancers." 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